-------------- The Truth About Nicotine By: Hwy9Vapor's DJ  --------------




An alarming amount of confusion seems to persist about the safety of nicotine. 

Due to its association with traditional cigarettes, many people still maintain the misconception that nicotine, 

rather than tobacco, is the culprit behind the many illnesses caused by smoking. 

But when you take a look at the science, this may not even be true; in fact, increasing evidence suggests 

that nicotine may actually help doctors treat neurological disorders such as depression, 

Alzheimer’s disease and Parkinson’s disease.




Could Nicotine Be The Next Wonder Drug?

Nicotine occurs naturally in tobacco, and other vegetation such as eggplants, squash,bacon potatoes etc..., but it can also be synthetically produced. 

It can be absorbed through the skin, mucous membranes in the mouth or the air sacs in the lungs. 

No matter how nicotine is consumed, it enters the bloodstream and travels to the brain where it binds to cholinergic receptors. 

Some governments around the world classify nicotine as poison because it can be toxic when ingested in large quantities in its pure form; however, no one drinks pure nicotine, so calling nicotine “poisonous” might be a little misleading. 

When smoking or chewing tobacco, users are consuming more chemicals than just nicotine, many of which are associated with cancer and other illnesses. Research on nicotine by itself, however, has revealed some potential therapeutic benefits.




The Connections Between Nicotine and Mental Health

In 2012, researchers at Vanderbilt University tested the effects of nicotine patches on non-smoking patients with mild cognitive impairment, which is often a precursor to Alzheimer’s disease. Half of participants wore a 15mg nicotine patch everyday for six months while the other half wore a placebo patch for the same amount of time. Tests measuring memory, attention span and speed of cognitive processing were given to all patients before and after treatment. Those who had the placebo performed about the same in both rounds of testing, but those who had nicotine showed substantial gains in all areas. Dr. Paul Newhouse, the study’s main author, concluded that the research “provides strong justification for further research into the use of nicotine for people with early signs of memory loss.”

Nicotine may also be an effective antidepressant; researchers at Duke University found that nicotine patches can reduce symptoms in depressed patients. They attributed their findings to nicotine’s ability to stimulate dopamine and serotonin release in the brain. Deficiencies in these two neurotransmitters are often linked to depression.

Dopamine also plays a role in locomotion, which is why nicotine is being investigated as a treatment for Parkinson’s disease. As far back as 1979, a researcher at UCLA discovered that nicotine increases levels of dopamine in the striatum, the part of the brain responsible for planning and controlling movement. Recent research on fruit flies at the Arizona College of Osteopathic Medicine led the head researcher to announce, “Nicotine treatment reduces or, in some instances, rescues different aspects of the Parkinson’s-associated phenotype when administered early.”

Because both Alzheimer’s and Parkinson’s increase oxidative stress, another study looked into nicotine’s use as an antioxidant. The researchers concluded that, “The beneficial/protective effects of nicotine in both Parkinson’s disease and Alzheimer’s disease may be, at least partly, due to antioxidant mechanisms.” The same study found that nicotine improved memory retention in rats. Another study on rodents suggests that nicotine boosts available levels of intracellular calcium, which can improve cellular survival. While this data is not an endorsement to start using nicotine like a multivitamin, it can help researchers develop ways to tap into nicotine’s full therapeutic potential.




How Addictive is Nicotine?

Debate surrounding nicotine’s addictive properties is now emerging thanks to findings such as those recently published in the peer-reviewed journal Tobacco Control. The authors of this study note that, “Nicotine is known as the drug that is responsible for the addictive behavior of tobacco users, but it has poor reinforcing effects when administered alone.” They investigated the addictive properties of pyrazines ( Pyrazine is a heterocyclic aromatic organic compound with the chemical formula C4H4N2. Pyrazine is a symmetrical molecule with point group D2h. Pyrazine is less basic than pyridine, pyridazine and pyrimidine. Derivatives such as phenazine are well known for their antitumor, antibiotic and diuretic activities.), one of the many additives commonly found in cigarette tobacco, and found that “such additives may enhance dependence by helping to optimize nicotine delivery and dosing.” In other words, nicotine alone doesn’t cause cigarette addiction, but the combination of nicotine and other additives along with the delivery method are the true culprits. It is also worth noting that no signs of withdrawal have been documented in humans or other animals after being administered nicotine for therapeutic purposes.

Nicotine in Tobacco vs. Nicotine in Vaping

When smoking a tobacco cigarette, nicotine, along with hundreds of other chemicals, gets released through combustion. E-cigs, on the other hand, heat a solution of nicotine in a medium such as propylene glycol to produce nicotine in vapor form. A comprehensive overview of literature comparing nicotine delivery via e-cigs and tobacco cigarettes revealed that e-cigs deliver less nicotine per puff than traditional cigarettes.Furthermore, many e-cig companies such as White Cloud allow users to control their nicotine intake with a selection of nicotine strengths, while traditional cigarettes offer no options to control the amount of nicotine delivered.




The Future of Nicotine

With the latest evidence suggesting electronic cigarettes are 98% less harmful than tobacco cigarettes, combined with the research findings of the therapeutic benefits of nicotine, it may be safe to say there is a brighter future for both e-cigs and nicotine Fact: Vaping has been out for over 13years. 

Perhaps e-cigs may even one day be prescribed to treat neurological disorders. This idea may not be so far-fetched when considering the fact that studies have yet to prove any negative side effects of e-cigs, compared to the long list of side effects that accompany the prescription medications currently used to treat such disorders. As a result, the concept of nicotine as a wonder drug should bring a sigh of relief to those deemed to be “nicotine addicts” as the research continues to prove nicotine may not be the enemy traditional cigarettes have portrayed it to be.




STUDIES SHOW THAT E-CIGARETTES  HOLD A HIGHER SUCCESS RATE AS A SMOKING CESSATION AID THAN QUITTING COLD TURKEY, NICOTINE GUM, AND NICOTINE PATCHES.

In the past, smokers faced a daunting question when it came to quitting smoking: How do you successfully quit?

The adverse effects of smoking are well known, yet the addictive qualities of traditional analog cigarettes have proven a formidable foe.  Quitting smoking has been the focus of numerous New Year’s resolutions, only to fail time and time again. When it comes to taking the leap, there are several severely limited methods from which to choose.




Methods




Quitting cold turkey. As many have come to find, this is one of the most difficult ways to quit smoking. In fact, it has proven impossible for many.
Nicotine gum. According to WebMD, and as its name describes, the gum contains small amounts of nicotine. This is supposed to ease your nicotine cravings when chewed. However, the small traces of nicotine is not enough to fully subdue the craving to smoke. It also does not address the “habit” aspect of smoking.
Nicotine patches. This method is based on sticking a large circular patch onto your skin – usually the upper arm. It is noted by WebMD that it releases nicotine in metered doses directly onto the skin where it absorbed into the bloodstream. This method also entails having a patch stuck to your body and does not address the aspect of smoking relating to the “habit”.

The “habit” of smoking is the actual actions your body makes during smoking. Having the cigarette between your fingers, the cigarette in your mouth, the inhaling and exhaling of the smoke. This aspect is the primary reason why these methods do not hold a high success rate or fail to work altogether. In fact, studies have shown that nicotine gum has a higher success rate than quitting cold turkey and that patches hold a higher success rate than that of nicotine gum. However, even at its highest margin of success, patches only resulted in a total 8.2% success rate for quitting smoking.




Electronic Cigarettes: Brief Overview




Electronic cigarettes, or e-cigarettes, are cigarette simulation apparatuses which combine the natural actions of smoking with the nicotine levels of your choice. They produce thick, rich nicotine-infused water vapor or mist which allows the user to enjoy the same smoking experience, without the 600 toxic ingredients and the subsequent 7,000 chemicals which are produced through the act of combustion (American Lung Association).

With numerous makes and models, Vaping simulates the smoking experience. It is a nicotine replacement system which allows the user to experience a different type of nicotine inhalation. They provide the same satisfaction, and continue by allowing the user greater control over the amount of nicotine they are actually consuming.

Further, the products do not rely on any form of combustion, which also produces large quantities of carbon monoxide. Instead, they rely on a heated coil which converts the flavored nicotine liquid into vapor, or mist. This is a highly coveted aspect of e-cigarettes among its millions of users. The vapor simulates, by look and feel, the smoke from an analogue cigarette with out all the harmful and fatal tar & chemicals.




Comparative Study

There are ongoing studies into the use of electronic cigarettes, but there is now evidence from a study in the UK which shows that e-cigarette use might have a 90% higher success rate for quitting smoking, compared to the patch, gum, or attempting to quit cold turkey.

A new study finds that, among people who are trying to quit without professional help, those who use electronic cigarettes are 90% more likely to succeed, compared with those who use willpower or nicotine replacement therapies.

Medical News Today




Outcome

To date, there has been no conclusive evidence submitted that demonstrates any form of adverse effects related to the use of e-cigarettes. More and more, studies are proving more information about the devices, and how they can successfully assist people in achieving their goals.







Motivation

Vaping users report several reasons for use:

Recreational use,
To cut down or quit smoking;
Changed my Life
Because they believe vaping is healthier than smoking;
To circumvent smoke-free laws and policies;
Because e-cigarettes are odor-free; or
Because vaping is better and cheaper.

Marketing aimed at smokers focuses on these motivations.[This marketing does influence people to try them.

When users were asked why they had first tried e-cigarettes, reasons given were curiosity or experimentation; because a relative/friend was using them and it works; or because they were given or offered one to help them quit smoking aswell.

Some researchers are concerned about vaping during pregnancy.

Some users have stopped vaping due to issues with the devices, Hwy9Vapor's DJ says "99% of the time user error and or something very simple and a easy fix."

 MOST say Dissatisfaction and concerns over safety ( Thanks CNN, Fox FDA, Cigarette Companies etc.It's all about $$$ Not the Publics Health in their eyes.. 

False Rumors can also discourage ongoing e-cigarette use. 




DJ says " Forget all the misleading rumors and lies, fact: every one knows some one whom vapes, ask them for their truthful testimony, 

"" Theirs No Truth in a Lie, and Theirs No Lie in the Truth  "" James DeLeo (aka) D.J."

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